protease-degradable custom synthesised peptide (vpm (GenScript corporation)
Structured Review

Protease Degradable Custom Synthesised Peptide (Vpm, supplied by GenScript corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/protease-degradable+custom+synthesised+peptide+%28vpm/pmc07866402-78-14-25?v=GenScript+corporation
Average 90 stars, based on 1 article reviews
Images
1) Product Images from "Dynamic Mechanical Control of Alginate-Fibronectin Hydrogels with Dual Crosslinking: Covalent and Ionic"
Article Title: Dynamic Mechanical Control of Alginate-Fibronectin Hydrogels with Dual Crosslinking: Covalent and Ionic
Journal: Polymers
doi: 10.3390/polym13030433
Figure Legend Snippet: Simplified sketch of covalently crosslinked alginate hydrogels with degradable or non-degradable crosslinks. ( a ) Norbornene-modified alginate hydrogels are formed by UV-initiated polymerisation using a thiolated crosslinker (dithithreitol, DTT, in red) or ( b ) a custom-synthesised thiolated protease-sensitive peptide (GCRDVPMSMRGGDRCG, VPM, in red, where R depicts the degradable peptide chain). ( c ) Additionally, alginate hydrogels can incorporate the full fibronectin protein by using maleimide functionalised PEGylated fibronectin (PEGylation using a 4-arm-PEG-maleimide, ratio 1:4 FN:PEGMAL) and a thiolated protease-sensitive peptide crosslinker. Note that both norbornene-thiol and maleimide-thiol reactions are stochastic and the sketches aim to represent the nature of the different crosslinking reactions, not the real final structure of the hydrogel.
Techniques Used: Modification