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protease-degradable custom synthesised peptide (vpm  (GenScript corporation)

 
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    Structured Review

    GenScript corporation protease-degradable custom synthesised peptide (vpm
    Simplified sketch of covalently crosslinked alginate hydrogels with degradable or non-degradable crosslinks. ( a ) Norbornene-modified alginate hydrogels are formed by UV-initiated polymerisation using a thiolated crosslinker (dithithreitol, DTT, in red) or ( b ) a <t>custom-synthesised</t> thiolated protease-sensitive peptide (GCRDVPMSMRGGDRCG, VPM, in red, where R depicts the degradable peptide chain). ( c ) Additionally, alginate hydrogels can incorporate the full fibronectin protein by using maleimide functionalised PEGylated fibronectin (PEGylation using a 4-arm-PEG-maleimide, ratio 1:4 FN:PEGMAL) and a thiolated protease-sensitive peptide crosslinker. Note that both norbornene-thiol and maleimide-thiol reactions are stochastic and the sketches aim to represent the nature of the different crosslinking reactions, not the real final structure of the hydrogel.
    Protease Degradable Custom Synthesised Peptide (Vpm, supplied by GenScript corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/protease-degradable+custom+synthesised+peptide+%28vpm/pmc07866402-78-14-25?v=GenScript+corporation
    Average 90 stars, based on 1 article reviews
    protease-degradable custom synthesised peptide (vpm - by Bioz Stars, 2026-07
    90/100 stars

    Images

    1) Product Images from "Dynamic Mechanical Control of Alginate-Fibronectin Hydrogels with Dual Crosslinking: Covalent and Ionic"

    Article Title: Dynamic Mechanical Control of Alginate-Fibronectin Hydrogels with Dual Crosslinking: Covalent and Ionic

    Journal: Polymers

    doi: 10.3390/polym13030433

    Simplified sketch of covalently crosslinked alginate hydrogels with degradable or non-degradable crosslinks. ( a ) Norbornene-modified alginate hydrogels are formed by UV-initiated polymerisation using a thiolated crosslinker (dithithreitol, DTT, in red) or ( b ) a custom-synthesised thiolated protease-sensitive peptide (GCRDVPMSMRGGDRCG, VPM, in red, where R depicts the degradable peptide chain). ( c ) Additionally, alginate hydrogels can incorporate the full fibronectin protein by using maleimide functionalised PEGylated fibronectin (PEGylation using a 4-arm-PEG-maleimide, ratio 1:4 FN:PEGMAL) and a thiolated protease-sensitive peptide crosslinker. Note that both norbornene-thiol and maleimide-thiol reactions are stochastic and the sketches aim to represent the nature of the different crosslinking reactions, not the real final structure of the hydrogel.
    Figure Legend Snippet: Simplified sketch of covalently crosslinked alginate hydrogels with degradable or non-degradable crosslinks. ( a ) Norbornene-modified alginate hydrogels are formed by UV-initiated polymerisation using a thiolated crosslinker (dithithreitol, DTT, in red) or ( b ) a custom-synthesised thiolated protease-sensitive peptide (GCRDVPMSMRGGDRCG, VPM, in red, where R depicts the degradable peptide chain). ( c ) Additionally, alginate hydrogels can incorporate the full fibronectin protein by using maleimide functionalised PEGylated fibronectin (PEGylation using a 4-arm-PEG-maleimide, ratio 1:4 FN:PEGMAL) and a thiolated protease-sensitive peptide crosslinker. Note that both norbornene-thiol and maleimide-thiol reactions are stochastic and the sketches aim to represent the nature of the different crosslinking reactions, not the real final structure of the hydrogel.

    Techniques Used: Modification



    Similar Products

    90
    GenScript corporation protease-degradable custom synthesised peptide (vpm
    Simplified sketch of covalently crosslinked alginate hydrogels with degradable or non-degradable crosslinks. ( a ) Norbornene-modified alginate hydrogels are formed by UV-initiated polymerisation using a thiolated crosslinker (dithithreitol, DTT, in red) or ( b ) a <t>custom-synthesised</t> thiolated protease-sensitive peptide (GCRDVPMSMRGGDRCG, VPM, in red, where R depicts the degradable peptide chain). ( c ) Additionally, alginate hydrogels can incorporate the full fibronectin protein by using maleimide functionalised PEGylated fibronectin (PEGylation using a 4-arm-PEG-maleimide, ratio 1:4 FN:PEGMAL) and a thiolated protease-sensitive peptide crosslinker. Note that both norbornene-thiol and maleimide-thiol reactions are stochastic and the sketches aim to represent the nature of the different crosslinking reactions, not the real final structure of the hydrogel.
    Protease Degradable Custom Synthesised Peptide (Vpm, supplied by GenScript corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/protease-degradable+custom+synthesised+peptide+%28vpm/pmc07866402-78-14-25?v=GenScript+corporation
    Average 90 stars, based on 1 article reviews
    protease-degradable custom synthesised peptide (vpm - by Bioz Stars, 2026-07
    90/100 stars
      Buy from Supplier

    90
    GenScript corporation protease-degradable custom synthesised peptide vpm
    Simplified sketch of covalently crosslinked alginate hydrogels with degradable or non-degradable crosslinks. ( a ) Norbornene-modified alginate hydrogels are formed by UV-initiated polymerisation using a thiolated crosslinker (dithithreitol, DTT, in red) or ( b ) a <t>custom-synthesised</t> thiolated protease-sensitive peptide (GCRDVPMSMRGGDRCG, VPM, in red, where R depicts the degradable peptide chain). ( c ) Additionally, alginate hydrogels can incorporate the full fibronectin protein by using maleimide functionalised PEGylated fibronectin (PEGylation using a 4-arm-PEG-maleimide, ratio 1:4 FN:PEGMAL) and a thiolated protease-sensitive peptide crosslinker. Note that both norbornene-thiol and maleimide-thiol reactions are stochastic and the sketches aim to represent the nature of the different crosslinking reactions, not the real final structure of the hydrogel.
    Protease Degradable Custom Synthesised Peptide Vpm, supplied by GenScript corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/protease-degradable+custom+synthesised+peptide+%28vpm/pmc07866402-78-13-25?v=GenScript+corporation
    Average 90 stars, based on 1 article reviews
    protease-degradable custom synthesised peptide vpm - by Bioz Stars, 2026-07
    90/100 stars
      Buy from Supplier

    Image Search Results


    Simplified sketch of covalently crosslinked alginate hydrogels with degradable or non-degradable crosslinks. ( a ) Norbornene-modified alginate hydrogels are formed by UV-initiated polymerisation using a thiolated crosslinker (dithithreitol, DTT, in red) or ( b ) a custom-synthesised thiolated protease-sensitive peptide (GCRDVPMSMRGGDRCG, VPM, in red, where R depicts the degradable peptide chain). ( c ) Additionally, alginate hydrogels can incorporate the full fibronectin protein by using maleimide functionalised PEGylated fibronectin (PEGylation using a 4-arm-PEG-maleimide, ratio 1:4 FN:PEGMAL) and a thiolated protease-sensitive peptide crosslinker. Note that both norbornene-thiol and maleimide-thiol reactions are stochastic and the sketches aim to represent the nature of the different crosslinking reactions, not the real final structure of the hydrogel.

    Journal: Polymers

    Article Title: Dynamic Mechanical Control of Alginate-Fibronectin Hydrogels with Dual Crosslinking: Covalent and Ionic

    doi: 10.3390/polym13030433

    Figure Lengend Snippet: Simplified sketch of covalently crosslinked alginate hydrogels with degradable or non-degradable crosslinks. ( a ) Norbornene-modified alginate hydrogels are formed by UV-initiated polymerisation using a thiolated crosslinker (dithithreitol, DTT, in red) or ( b ) a custom-synthesised thiolated protease-sensitive peptide (GCRDVPMSMRGGDRCG, VPM, in red, where R depicts the degradable peptide chain). ( c ) Additionally, alginate hydrogels can incorporate the full fibronectin protein by using maleimide functionalised PEGylated fibronectin (PEGylation using a 4-arm-PEG-maleimide, ratio 1:4 FN:PEGMAL) and a thiolated protease-sensitive peptide crosslinker. Note that both norbornene-thiol and maleimide-thiol reactions are stochastic and the sketches aim to represent the nature of the different crosslinking reactions, not the real final structure of the hydrogel.

    Article Snippet: Two different types of crosslinkers were used—either dithiothreitol (DTT, Sigma-Aldrich, Eppelheim, Germany) or protease-degradable custom synthesised peptide (VPM, GCRDVPMSMRGGDRCG, purity 96.9%, M w 1696.96 Da, GenScript, Leiden, The Netherlands).

    Techniques: Modification